intermittent exotropia
Conditions
Interventions
Healthy control group:nil
Sponsors
Beijing Tongren Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Surgical treatment group: 1)Age between18 and 60 years; 2)Evidence of IXT on the basis of history and clinical examination; 3)Have surgical intention and meet the surgical indications including: loss of distant stereopsis using synoptophore and/or deflection time accounts for more than half of waking time; angle of deviation< -15?; 4)No ongoing or planned amblyopia treatment; 5)Binocular best corrected visual acuity (BCVA)=1.0, no anisometropia (binocular diopter difference < 2.5DS); 6)Right handedness; 7)Be able to understand and cooperate with examinations, sign informed consent voluntarily. Healthy control group: 1)Age between 18 and 60 years; 2)BCVA=1.0 and free of any ocular diseases; 3)Right handedness; 4)Be able to understand and cooperate with examinations, sign informed consent voluntarily.
Exclusion criteria
Exclusion criteria: Subjects who meet the inclusion criteria will be excluded if they meet any of the following criteria. 1)Have organic eye disease; 2)Previous eye surgery history; 3)Accompanied by vertical strabismus; 4)History of diseases of central nervous system and whole body; 5)Contraindication for MRI examination (treatable or accidental magnetizable metal in cardiac pacemaker or prosthesis or previous head or spinal trauma requiring neurosurgery, etc.); 6)Claustrophobia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| BOLD-fMRI; | — |
Secondary
| Measure | Time frame |
|---|---|
| ocular motility;deviation degree;Ocular dominance;distance stereopsis;accommodative convergence/accommodation (AC/A) ratio;near stereopsis;Visual perception examination;Newcastle Control Score evaluation; | — |
Countries
China
Contacts
Public ContactFu Jing
Beijing Tongren Hospital
Outcome results
None listed