Effect of high flow nasal cannula on severe asthma patients with respiratory failure

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900027507

Enrollment

Unknown

Registered

2019-11-17

Start date

2017-06-01

Completion date

Unknown

Last updated

2019-11-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

bronchial asthma

Interventions

Experimental group:High Flow Nasal Cannula oxygen

Control group:conventional oxygen therapy

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) according to Gina diagnostic criteria, acute attack of severe bronchial asthma was determined; (2) according to blood gas analysis on admission, PO2 =45mmhg under the condition of air inhalation.

Exclusion criteria

Exclusion criteria: Immediate tracheal intubation, myocardial infarction (cardiothoracic pain with ECG changes or elevated myocardial enzyme level), disturbance of consciousness, hemodynamic damage (blood pressure 45 times / min, pH < 7.30, untreated pneumothorax, end-stage renal disease (estimated renal glomerular filtration rate of less than 15ml / min or dialysis per 1.73m2), contraindications of using positive airway pressure equipment, with Pneumonia.

Design outcomes

Primary

Measure	Time frame
Effective rate;	—

Countries

China

Contacts

Public ContactGeng Wanru

Department of Respiratory and Critical Care Medicine, Affiliated Hospital of Tongliao University for nationalities, Inner Mongolia Autonomous Region

geng-wanru@163.com+86 13847521595

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026