Application of ultrasound - guided transabdominis plane combined with rectus sheath nerve block in anesthesia of kidney transplantation

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900027495

Enrollment

Unknown

Registered

2019-11-16

Start date

2020-05-06

Completion date

Unknown

Last updated

2021-05-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

end stage renal disease

Interventions

Nerve block group:Ultrasound guided inferior transverse abdominal nerve block combined with rectus abdominis nerve block (ropivacaine)

control group:Ultrasound-guided horizontal nerve block of inferior transverse abdominis combined with rectus sheath nerve block (normal saline)

Eligibility

Sex/Gender

All

Age

20 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1. The enrolled patients were aged 20-50 years; 2. Sign informed consent; 3. ASA III-IV?; 4. Perfect preoperative examination, composite kidney transplantation operation indication.

Exclusion criteria

Exclusion criteria: 1. Patients with poor general condition and unsuitable for surgery, severe cardiac and pulmonary dysfunction, and insufficiency of vital organ and palace functions, are difficult to tolerate surgery; Severe anemia. 2. Abnormal coagulation, respiratory failure, and a history of previous kidney transplantation. 3. Communication disorders (language/physical defects/culture) affect information collection. 4. Puncture site/site to block - peripheral neuropathy or sensory abnormalities in the innervated skin area. 5. There is infection at the puncture site. 6. For patients with previous abdominal surgery, surgical sores may affect the spread of local anesthetics. 7. Patients allergic to lorazepam or dexmedetomidine.

Design outcomes

Primary

Measure	Time frame
Intraoperative anesthetic dosage;	—

Secondary

Measure	Time frame
Intraoperative hemodynamic parameters;The earliest distance between pressing the analgesic pump and pulling the tube after operation;Total number of analgesic pump presses within 3 days after surgery;Total number of effective times of analgesic pump press 3 days after operation;Postoperative 1-3 to sleep quality evaluation;Delirium evaluation 1-7 days after surgery;Postoperative pain VAS assessment;Use of remedial analgesics in the postoperative ward;	—

Measure

Time frame

Intraoperative hemodynamic parameters;The earliest distance between pressing the analgesic pump and pulling the tube after operation;Total number of analgesic pump presses within 3 days after surgery;Total number of effective times of analgesic pump press 3 days after operation;Postoperative 1-3 to sleep quality evaluation;Delirium evaluation 1-7 days after surgery;Postoperative pain VAS assessment;Use of remedial analgesics in the postoperative ward;

—

Countries

China

Contacts

Public ContactGuanghong Xu

Department of Anesthesiology, the First Affiliated Hospital of Anhui Medical University

xuguanghong2004@163.com+86 13856949535

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026