Clinical observation of dexmedetomidine combined with sufentanil on postoperative analgesia in elderly patients with TURP

Analgesia and safety evaluation of dexmedetomidine combined with sufentanil for postoperative analgesia in elderly patients undergoing transurethral bladder or prostate surgery under general anesthesia

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900027481

Enrollment

Unknown

Registered

2019-11-15

Start date

2019-12-02

Completion date

Unknown

Last updated

2019-11-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

TURP

Interventions

control group:sufentanyl

experimental group:dexmedetomidine+sufentanyl

Eligibility

Sex/Gender

All

Age

60 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Elderly patients undergoing elective transurethral bladder or prostate surgery; 2. ASA I - III level; 3. Aged >= 60 years, gender not limited; 4. 30Kg/m2 >= BMI > 18Kg/m2; 5. General anesthesia; 6. Normal communication and proper use of PCA device; 7. Agree to participate in experimental observation and sign informed consent.

Exclusion criteria

Exclusion criteria: 1. People who are known to be allergic to dexmedetomidine; 2. Long-term use of analgesics, sedatives or non-steroidal anti-inflammatory drugs; 3. Previous history of neuromuscular disease; 4. Previous history of endocrine diseases; 5. Previous allergic disease history; 6. Previous history of mental illness; 7. Previous abnormal cardiac conduction or rhythm; 8. Requires epidural anesthesia; 9. Recently participated in other drug clinical researchers; 10. The researchers do not think it is appropriate to participate in drug trials.

Design outcomes

Primary

Measure	Time frame
pain;PCA demand times;	—

Countries

China

Contacts

Public ContactZou Xiaohua

Affiliated Hospital of Guizhou Medical University

439375785@qq.com+86 13809416036

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026