clinical study on the effect of cranioplasty with autogenous bone flaps which preserved in vitro

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900027471

Enrollment

Unknown

Registered

2019-11-14

Start date

2019-12-01

Completion date

Unknown

Last updated

2019-11-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cranioplasty of skull defect

Interventions

1:The cranioplasty with autogenous bone flaps which preserved in vitro

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Adult patients (18 years and over) who were diagnosed as traumatic brain injury by clinical examination and CT scan. 2. The patients with traumatic brain injury should be treated with craniotomy, and decompressive craniectomy should be performed at the same time.

Exclusion criteria

Exclusion criteria: 1. The patients who haven't been removed the bone flaps. 2. The patients with opened injury and contaminated severely. 3. The patients with comminuted skull fracture. 4. The patients with severe injury, GCS3, bilateral pupils dilated, and severe multiple trauma who are cured hopeless. 5. The patients whose bone flaps can't meet the requirements of later repair (for example :bone defect larger than 2cm when reimplantation , skull lesions).

Design outcomes

Primary

Measure	Time frame
clinical efficacy;	—

Secondary

Measure	Time frame
Complication;	—

Countries

China

Contacts

Public ContactChaohua Yang

yangchaohua999@126.com+86 18980602030

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026