Study on the molecular mechanism of association between adipocytokines and intestinal flora in depression

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR1900027456

Enrollment

Unknown

Registered

2019-11-14

Start date

2019-11-06

Completion date

Unknown

Last updated

2019-11-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression

Interventions

Health control group:N/A

Depressive episode with standardize therapy group:N/A

Depressive episode with standardize therapy combined with Probiotics:N/A

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Meets the diagnostic criteria for First or recurrence DSM-V depression; 2. Aged between 15 and 50 years; 3. Did not take any antidepressants treatment and other antipsychotics within 12 weeks before enrollment.

Exclusion criteria

Exclusion criteria: 1. Schizophrenia and other mental diseases; 2. History of alcohol or other substance dependence abuse; 3. History of cardiovascular, lung, kidney, liver, brain, digestive system endocrine system and other systemic diseases; 4. Hemograms, liver orkidney function abnormal; 5. Women during pregnancy and lactation; 6. History of Mania or hypomania; 7. Inflammatory diseases or received antibiotics within recent.

Design outcomes

Primary

Measure	Time frame
Hamilton Depression Rating Scale (HAMD);Gut microbiota;Adipokines;	—

Countries

China

Contacts

Public ContactCao Meiqun

Shenzhen Second People's Hospital

mqcao111@163.com+86 0755-83200019

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026