Prostate Caner
Conditions
Interventions
experimental group:TURP combined with ADT
controlled group:ADT
Sponsors
Fudan University Shanghai Cancer Center
Eligibility
Sex/Gender
Male
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Male; 2. Aged >=18, = 2, endless urination, urine waiting, indwelling catheterization, cystotomy due to dysuria, Qmax 2 year2; 9. No prior local treatment to prostate and metastatic lesion; 10. The primary lesion of prostate could be treated by TURP without severe complications including death, incontinence, rectal injury and life-threatening bleeding; 11. Voluntary participation and informed consent signed; 12. Patients could be treated and followed up regularly.
Exclusion criteria
Exclusion criteria: 1. Prior treatment to primary lesion including radical prostatectomy, TURP, radiation therapy, cryoablation, HIFU, irreversible electroporation; 2. History of chemotherapy or ADT > 6 months; 3. Small cell carcinoma of the prostate; 4. Poor physical condition and intolerant to the treatment of primary lesion; 5. Unwilling to take the risks of complications brought by the treatment to primary lesion or metastatic lesion 6. History of other malignant tumors (excluding basal cell carcinoma or other tumors cured for over 5 years); 7. Other severe conditions; 8. Enrolled in other trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| progression of primary lesion;Local symptom; | — |
Secondary
| Measure | Time frame |
|---|---|
| PSA progression;Overall survival;PSMA-based nuclear imaging; | — |
Countries
China
Contacts
Public ContactDingwei Ye
Fudan University Shanghai Cancer Center
Outcome results
None listed