lung cancer
Conditions
Interventions
control group:chemotherapy
Sponsors
Dongfang Hospital Beijing University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: (1) Patients with histologically or cytologically confirmed NSCLC, and clinical stage IIIb or IV. (2) One of above five TCM syndrome pattern differentiation; (3) There is at least one lesion larger than 2cm in diameter that can be cryoablation in the lung; (4) The Eastern Cooperative Oncology Group (ECOG) score <= 2 and the expected survival time was more than 3 months (5) Aged more than 18 years; (6) Able to read Chinese and willingness to provide signed informed consent.
Exclusion criteria
Exclusion criteria: (1) Patients who had received any radiation, chemotherapy, targeted therapy or immunotherapy for their cancers within a month; (2) Patients with symptomatic brain metastases; (3) Patients with infectious and radioactive inflammation around the lesion, or skin infection and ulceration at the puncture site; (4) Patients with severe pulmonary fibrosis especially drug-induced pulmonary fibrosis; (5) Patients with severe bleeding tendency, platelet less than 50×109/L and severe coagulation disorders; (6) Patients with poor control of ipsilateral malignant pleural effusion; (7) Pregnant and lactating women; or severe insufficiency of liver, kidney, heart, lung and brain; or severe anemia, dehydration and serious disorders of nutrition metabolism, unable to be corrected or improved in a short time; or patients with severe systemic infection and high fever (T > 38.5 degree C). (8) HIV antibody positive or with other acquired or congenital immunodeficiency diseases; (9) Patients with a history of organ transplantation; (10) Patients enrolled in other clinical trials within three months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| overall survival time; | — |
Countries
China
Contacts
Public ContactKaiwen Hu
IRB of Dongfang Hospital Beijing University of Chinese Medicine
Outcome results
None listed