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A real-world multi-center cross-sectional study of Nipple-sparing mastectomy in early breast cancer organized by Chinese Medical Association Surgery Branch Breast Surgery Group

A real-world multi-center cross-sectional study of Nipple-sparing mastectomy in early breast cancer organized by Chinese Medical Association Surgery Branch Breast Surgery Group

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900027423
Enrollment
Unknown
Registered
2019-11-12
Start date
2018-01-01
Completion date
Unknown
Last updated
2021-07-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast Tumor

Interventions

Case series:None

Sponsors

First Medical Center of Chinese PLA general hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
22 Years to 64 Years

Inclusion criteria

Inclusion criteria: 1. Invasive breast cancer, Ductal Carcinoma In Situ, Breast Related Cancer antigens mutation carriers; 2. Aged 18 Years and older; 3. Candidates to nipple-sparing mastectomy and immediate breast reconstruction; 4. Negative preoperative assessment of nipple-areola complex; 5. Absence of skin involvement; 6. Breast volume 20 cigarettes/day); 8. Low and intermediate risk for anesthesia (ASA Scale); 9. Written informed consent must be signed and dated by the patient and the investigator prior to inclusion; 10. Patients must be accessible for follow-up.

Exclusion criteria

Exclusion criteria: 1. Previous thoracic radiation therapy for any reason; 2. Inflammatory Breast Cancer; 3. Skin involvement; 4. Pre-operative diagnosis (radiological or pathological) of nipple-areola complex disease; 5. Pregnancy; 6. Patients with psychiatric, addictive, or any disorder, which compromises ability to give informed consent for participation in this study; 7. High risk for anesthesia.

Design outcomes

Primary

MeasureTime frame
Operation status;

Secondary

MeasureTime frame
Surgical safety;

Countries

China

Contacts

Public ContactWang Jiandong

First Medical Center of Chinese PLA general hospital

wangjiandong@188.com+86 13910269069

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 16, 2026