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Effects of ginkgo diterpene lactone on cognitive function and brain magnetic resonance structure and functional connections in mild cognitive impairment

Effects of ginkgo diterpene lactone on cognitive function and brain magnetic resonance structure and functional connections in mild cognitive impairment

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900027411
Enrollment
Unknown
Registered
2019-11-12
Start date
2020-01-01
Completion date
Unknown
Last updated
2019-11-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mild cognitive impairment

Interventions

General treatment group:Ginkgo biloba lactone and basic treatment
Control group:Basic treatment

Sponsors

The Affiliated Suzhou Science & Technology Town Hospital of Nanjing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. in line with MCI diagnostic criteria; 2. aged >= 60 years old; 3. informed consent, volunteer to participate.

Exclusion criteria

Exclusion criteria: 1. Hypertensive patients with uncontrollable blood pressure (systolic blood pressure greater than 160mmHg or diastolic blood pressure greater than 100mmHg); 2. have a history of alcohol and drug abuse; 3. have a history of mental illness (such as personality disorder, schizophrenia, etc.), or have severe aphasia and audio-visual disorders, or severe organ failure, history of myocardial infarction, history of coronary heart disease, musculoskeletal disorders and other contraindications; 4. cognitive impairment caused by depression, that is, the old age depression scale (ODS) >= l1; 5. people with cognitive impairment caused by drugs or poisoning; 6. are participating in other clinical trials that influence the evaluation of the results of this study.

Design outcomes

Primary

MeasureTime frame
Cognitive state;Depressed state;Daily life scale;Tinetti gait and balance test;

Countries

China

Contacts

Public ContactCai Zenglin

The Affiliated Suzhou Science & Technology Town Hospital of Nanjing Medical University

caizengling@163.com+86 19951296073

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026