Clinical study of modified curettage for medication-related osteonecrosis of the jaw

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900027382

Enrollment

Unknown

Registered

2019-11-11

Start date

2019-11-01

Completion date

Unknown

Last updated

2019-11-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

medication-related osteonecrosis of the jaw, MRONJ

Interventions

group1:curettage

group2:curretage plus bone tunnel preparation

Eligibility

Sex/Gender

All

Age

25 Years to 100 Years

Inclusion criteria

Inclusion criteria: According to the MRONJ diagnosis standard; stratified into stage II; general body condition can tolerate surgery; agree to receive curettage surgery; sign informed consent.

Exclusion criteria

Exclusion criteria: Preoperative diagnosis as MRONJ, but the postoperative specimen was diagnosed as metastatic tumor; the follow-up of the patient was lost after surgery.

Design outcomes

Primary

Measure	Time frame
Status evaluation of bone exposure or mucosa/skin fistula;Status evaluation of bone exposure or mucosa/skin fistula;Status evaluation of bone exposure or mucosa/skin fistula;bony wound healing;	—

Secondary

Measure	Time frame
University of Washington Quality of Life Questionnaire (UW-QOL, V4.0);University of Washington Quality of Life Questionnaire (UW-QOL, V4.0);	—

Countries

China

Contacts

Public ContactGuo Yuxing

Peking University Hospital of Stomotology

gladiater1984@163.com+86 15101126779

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026