Cirrhotic portal hypertension
Conditions
Interventions
A:Oral carvedilol
B:PSE
Sponsors
Shandong Provincial Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Diagnosed as cirrhosis, including pathological diagnosis or clinical and imaging confirmation; 2. Endoscopy confirmed the presence of esophageal and gastric varices; 3. HVPG >= 10mmHg; 4. Aged between 18 and 75 years; 5. Have good compliance with the proposed treatment requirements; 6. Obtain the subject's informed consent form.
Exclusion criteria
Exclusion criteria: 1. History of rupture of esophagogastric varices; 2. Esophageal varices have included endoscopic treatment, NSBB, TIPS or surgical treatment; 3. Carvedilol or PSE contraindications; 4. Confirm malignant tumors including hepatocellular carcinoma or other diseases that will shorten the lifespan of patients; 5. Cardiopulmonary failure; 6. The subject refuses to participate in the trial or does not have the ability to sign informed consent; 7. Pregnant or lactating women; 8. Researchers believe that poor compliance.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HVPG;Bleeding rate; | — |
Countries
China
Contacts
Public ContactChunqing Zhang
Shandong Provincial Hospital
Outcome results
None listed