cerebral small vessel disease
Conditions
Interventions
experimental group:ginkgo diterpene lactone combined with basic treatment
control group:basic treatment
Sponsors
Suzhou Science and Technology City Hospital
Eligibility
Sex/Gender
All
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) Age between 50 and 80 years old; 2) Meet the diagnostic criteria for cerebral small vessel disease; 3) MRI results meet the changing characteristics of LA, and patients with moderate or severe leukoaraiosis (Fazekas grade 2-3) are the subjects of study; 4) Check cooperation; 5) Those who signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1) History of neurological diseases (such as cerebral infarction, cerebral hemorrhage, multiple sclerosis, Alzheimer's disease), history of psychosis, history of drug and alcohol dependence, carbon monoxide poisoning, and other organic diseases that can cause cognitive decline; 2) White matter lesions caused by diseases of immune diseases, inflammation, tumors, poisoning, and closed brain damage; 3) Angiography confirmed the presence of large blood vessel stenosis in the skull; 4) Allergic to allergies or ginkgo diterpene lactone; 5) Those with serious heart, liver, kidney, hematopoietic diseases and thyroid diseases; 6) Can not perform head MR.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MMSE scale;MoCA scale;HAMD scale;ADL scale;Tinetti gait and balance test;Magnetic resoance examination; | — |
Countries
China
Contacts
Public ContactCai Zengling
Suzhou Science and Technology City Hospital
Outcome results
None listed