Behcet's disease
Conditions
Interventions
Behcet's disease group:Behcet??
Sponsors
Zunyi Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients who meet the diagnosis of Behcet's disease. Adopt the international classification criteria developed by the International Behcet's Research Group in 1990: (1) Repeated oral ulcers: Some doctors observed or patients complained of aphthous ulcers or scars, repeated attacks within >= 3 times a year. (2) Repeated genital ulcers: A doctor observed or the patient complained of genital aphthous ulcers, especially men. (3) Eye lesions: pre- and/or posterior uveitis, cell infiltration, or retinal vasculitis may be seen in the vitreous during slit lamp examination. (4) Skin lesions: nodular erythematous lesions, pseudo folliculitis, purulent papules, acne-like rash (appeared without taking glucocorticoids). (5) Acupuncture reaction positive: 20 ml sterile needle, obliquely inserted into the skin, 24-48 hours later by the doctor to determine the results. Anyone with repeated oral ulcers accompanied by 2 of the remaining 4 items can be diagnosed with this disease.
Exclusion criteria
Exclusion criteria: Other diseases (infections, tumors, and other autoimmune diseases) cause symptoms similar to Behcet's disease. Severe heart disease, cardiac insufficiency, liver dysfunction, renal insufficiency, respiratory failure, malignant tumor, gastrointestinal bleeding, etc. are not expected to complete the follow-up plan; patients with mental illness; other reasons can not take the drug on time; pregnancy and lactation Women; patients who are participating in other clinical trials; the researchers believe that other reasons are not suitable for clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Genetic markers;Cytokine;mRNA;Immune-related factor;DNA methylation;Non-coding RNA;Copy number variations;Immune cell ratio detection;Antinuclear antibody;Anti-endothelial cell antibody; | — |
Countries
China
Contacts
Public ContactHongsong Yu
Zunyi Medical University
Outcome results
None listed