Comparison of effects of intravenous remifentanil and sufentanil with etomidate on the incidence of hypotension after induction in elderly patients under general anesthesia

Comparison of effects of introvenous remifentanil and sufentanil with etomidate on the incidence of hypotension after induction in elderly patients under general anesthesia

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900027271

Enrollment

Unknown

Registered

2019-11-07

Start date

2019-11-11

Completion date

Unknown

Last updated

2019-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hypotension after induction under general anesthesia

Interventions

A:Sufentanil plus etomidate

B:Remifentanil plus etomidate

Eligibility

Sex/Gender

All

Age

65 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. ASA I-III grade 2. Aged over 65 years 3. General anesthesia, oral intubation

Exclusion criteria

Exclusion criteria: 1. Anaphylaxis to propofol, etomidate or other drugs used in this study; 2. Patients with respiratory system infection, asthma and other lung diseases; 3. Patients with severe liver and kidney dysfunction; 4. Patients with moderate and severe carotid artery stenosis; 5. Severe sinus bradycardia (HR <50 beats/ min) and second degree atrioventricular block.

Design outcomes

Primary

Measure	Time frame
incidence of hypotension after induction;heart rate after intubation;blood pressure after intubation;	—

Secondary

Measure	Time frame
number of cases of propofol after intubation;number of cases of pressor drugs;	—

Countries

China

Contacts

Public ContactYonghua Li

Department of Anesthesiology, Shanghai Changzheng Hospital

liyonghua1207@126.com+86 13795439726

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026