Cerebral small vessel Disease
Conditions
Interventions
Case series:Nil
Sponsors
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Age
55 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Aged 55-85 year old community population; 2. Sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Significantly limited independent living ability (MRS >=4); 2. Parkinson's disease, Alzheimer's disease and other progressive diseases of nervous system; 3. Severe depression (PHQ-9 >=20); 4. Serious mental disorders such as schizophrenia; 5. Other non vascular diseases that cause leukoencephalopathy, including CO poisoning, multiple sclerosis and adrenoleukodystrophy; 6. Cerebral hemorrhage, subarachnoid hemorrhage, intracranial space occupying lesions and other diseases; Acute ischemic stroke with infarction more than 2cm; 7. The expected service life is less than 1 year; 8. Obvious hearing or vision impairment, language disorder, claustrophobia, etc. and patients who can not cooperate with neuropsychological scale evaluation and MRI examination; 9. Patients who could not be followed up during the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Demographic data;Past history and risk factors;Medication situation;Personal habits;family history;Imaging data;physical examination;Assessment of daily living ability;Overall Cognitive Test and Dementia Assessment;Subdomain Cognitive Test;Psychological test;Gait assessment; | — |
Countries
China
Contacts
Public ContactXiang Luo
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Outcome results
None listed