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Clinical indicators and technical screening of opioid related immunosuppression on perioperative period

Clinical indicators and technical screening of opioid related immunosuppression on perioperative period

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900027208
Enrollment
Unknown
Registered
2019-11-05
Start date
2019-10-31
Completion date
Unknown
Last updated
2019-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lung cancer

Interventions

PVB group:25-30ug sufentanil during operation +T2 PVB
control group:Perioperative conventional sufentanil dosage

Sponsors

Chongqing Cancer Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1) Agree to join the study and obtain informed consent; 2) Aged between 30-75 years; 3) BMI < 30 4) American Society of Anesthesiologists (ASA) Classification I-III; 5) Diagnosis of lung cancer in hospital, receiving thoracoscopic radical resection of lung cancer.

Exclusion criteria

Exclusion criteria: 1) T2 paravertebral block can not be performed for various reasons; 2) Patients with coagulation dysfunction or receiving anticoagulation therapy; 3) Persons with a history of upper limb nerve injury or phrenic nerve injury; 4) Compound injury; 5) Preoperative Pulse Oxygen Saturation(SPO2)180 mmHg or diastolic blood pressure>110 mmHg) 7) Uncontrolled coronary heart disease, valvular heart disease and arrhythmia before operation; 8) Any reason that causes nerve block impossible to be performed (e.g. local infection at puncture site, swelling, unable to change position, etc.); 9) Fail to communicate or cooperate (mental retardation, Alzheimer, Parkinson, etc.); 10) Be allergic to ropivacaine or has other contraindications for nerve block.

Design outcomes

Primary

MeasureTime frame
NLR;Cell index function;

Secondary

MeasureTime frame
Dosage of remedial analgesics;QoR-40;

Countries

China

Contacts

Public ContactBin Yang

Department of Anesthesiology, Chongqing Cancer Hospital

yangbin4332@outlook.com+86 18581288032

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026