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A multicenter, randomized, single-blind, controlled trial for the effect of beclomethasone dipropionate suspension on the incidence of perioperative complications in patients with COPD lung cancer undergoing VATS lobectomy

A multicenter, randomized, single-blind, controlled trial for the effect of beclomethasone dipropionate suspension on the incidence of perioperative complications in patients with COPD lung cancer undergoing VATS lobectomy

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900027198
Enrollment
Unknown
Registered
2019-11-04
Start date
2017-05-01
Completion date
Unknown
Last updated
2019-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with COPD lung cancer need to receive VATS lobectomy

Interventions

Experimental group:Beclometasone Dipropionate Suspension for Inhalation

Sponsors

Tianjin Chest Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients understand the test procedures and the risks involved in the test, and voluntarily sign informed consent to participate; 2. Patients with newly diagnosed or existing COPD (according to the standard of "guidelines for diagnosis and treatment of COPD 2013 revision"), with FEV1 =90%; 7. Hemoglobin >=100G/L; 8. The estimated operation time is <=4 hours.

Exclusion criteria

Exclusion criteria: 1. Pregnant or lactating women; 2. Patients need pneumonectomy or intraoperative frozen pathology suggesting benign; 3. The patient had a history of acute exacerbation of COPD within 3 months before the visit; 4. The patient has a history of asthma; 5. The patient had pneumonia within 1 month before the visit; 6. The patient had a history of cerebral infarction, myocardial infarction, heart failure, severe arrhythmia and tuberculosis within 6 months before the visit; 7. Confirmed or suspected HIV infection; 8. The patient has cataract and glaucoma; 9. Allergy to any experimental drug or excipient; 10. The patient participated in any other study trial within 30 days prior to visit 1; 11. In the investigator's judgment, there are any diseases or conditions that may pose a risk to the patient or hinder participation in the trial.

Design outcomes

Primary

MeasureTime frame
Incidence of pulmonary complications (PPC);

Countries

China

Contacts

Public ContactXun zhang

Tianjin Chest Hospital

link_du@outlook.com+86 15922085014

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026