Moyamoya disease
Conditions
Interventions
Group D:Desflurane for anesthesia maintenance
GroupP:Propofol
GroupPD:Desflurane and propofol
Sponsors
The First Affiliated Hospital of Zhengzhou University
Eligibility
Sex/Gender
All
Age
20 Years to 65 Years
Inclusion criteria
Inclusion criteria: Aged 20-65 years; BMI 18-25kg/m2; ASA I-II grade; patients without hypertension or with hypertension history and satisfactory blood pressure control; patients without diabetes or with diabetes history and satisfactory blood glucose control.Hemoglobin (HB) >= 100g / L, hematocrit (HCT) >= 30%; no coagulation dysfunction, no long-term history of antidepressant and analgesic drugs
Exclusion criteria
Exclusion criteria: Patient or his family refused to sign the informed consent form and patients with liver and kidney function abnormality, lung function abnormality, serious coronary heart disease, serious endocrine disease, mental disease, drug abuse, coagulation function abnormality, unconsciousness, organ intubation difficulty, and severe fluctuation of hemodynamics during operation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Artefiovenous oxygen content difference;Cerebral oxygen extraction rate;Jugular venous blood oxygen saturation;Complication;GluERMB;LacPR;LOI;mRS score;NSE;S100ß protein; | — |
Secondary
| Measure | Time frame |
|---|---|
| Mean arterial pressure; | — |
Countries
China
Contacts
Public ContactWang Zhongyu
The First Affiliated Hospital of Zhengzhou University
Outcome results
None listed