Conjunctival Microbiome Changes After Long-Time Rigid Gas Permeable Contact Lens and Orthokeratology Lens Wearing

Effects of rigid air permeable contact lens and corneal plastic lens on conjunctival microorganisms

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR1900027193

Enrollment

Unknown

Registered

2019-11-04

Start date

2019-10-23

Completion date

Unknown

Last updated

2020-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

wear RGP and OK lens at least two years

Interventions

OK group vs. RGP group vs. Healthy people without contact lenses.:N/A

Eligibility

Sex/Gender

All

Age

10 Years to 30 Years

Inclusion criteria

Inclusion criteria: Continuous wearing with sequence or OK mirror for more than 2 years.

Exclusion criteria

Exclusion criteria: 1. had ocular or systemic diseases, ocular traumas, transplantations, or laser surgery; 2. recently had (within the previous 6 months) taken antibiotic and/or steroid treatment; 3. had allergies to drugs, pollen.

Design outcomes

Primary

Measure	Time frame
relative abundance and taxonomy;	—

Countries

China

Contacts

Public ContactDu Xianli

Shandong Eye Instiute, Qingdao Eye Hospital

lilibestever@126.com+86 15192552255

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026