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Application of tissue oxygenation as a target for goal-directed haemodynamic management in elderly patients orthopedic surgery

Application of tissue oxygenation as a target for goal-directed haemodynamic management in elderly patients orthopedic surgery

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900027190
Enrollment
Unknown
Registered
2019-11-04
Start date
2020-01-01
Completion date
Unknown
Last updated
2019-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

orthopedic surgery

Interventions

Intervention group:intervention guided by Tissue oxygenation

Sponsors

The First Affiliated Hospital of Zhengzhou University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
61 Years to No maximum

Inclusion criteria

Inclusion criteria: 1) Aged > 60 years; 2) ASA classification I-III; 3) Undergoing elective lumbar surgery under general anesthesia.

Exclusion criteria

Exclusion criteria: 1) Refusal to participate in this study; 2) Emergency surgery; 3) Anemia; 4) Preoperative chemotherapy or radiotherapy; 5) Neurological or psychiatric disorders cannot be accepted after surgery; 6) Heart, lung, liver and kidney dysfunction; 7) Severe skeletal muscle diseases such as muscle atrophy; 8) Skin disease can not tolerate non-invasive electrode pads.

Design outcomes

Primary

MeasureTime frame
Hemodynamic index;tissue oxygen saturation;Postoperative Simple Mental State Examination Scale (MMSE) Score;Postoperative complications such as hyperlacticemia, lower extremity venous thrombosis, pulmonary embolism, cerebral infarction, nausea and vomiting, and postoperative cognitive impairment occurred during hospitalization and 30 days after operation;The patient's awake time, extubation time, and immediate OAA/S score after extubation;Intraoperative lactate level;

Secondary

MeasureTime frame
PACU stay time, hospital stay;First activity time after surgery;

Countries

China

Contacts

Public ContactAi Yanqiu

The First Affiliated Hospital of Zhengzhou University

aiyanqiu82@163.com+86 13027501732

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026