Lung cancer
Conditions
Interventions
Index test:The 
risk 
assessment 
model 
of 
lung 
cancer 
for 
population.
Sponsors
The First Affiliated Hospital, Zhejiang University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. aged 18-75 years; 2. at least one of the following risk factors should be combined: (1) smoking 20 packages year, including those who used to smoke, but quit less than 15 years; (2) passive smokers;(note: long-term passive smoking refers to the continuous smoke >= 0.5h/d for 5 years when there are smokers in the family or the same room); (3) occupational exposure history (asbestos, beryllium, uranium, radon and other contacts); (4) have a family genetic history of malignant tumors or a family history of lung cancer; (5) have a history of COPD, diffuse pulmonary fibrosis, tuberculosis, chronic pneumonia, asthma and other diseases.
Exclusion criteria
Exclusion criteria: 1. Serum samples with severe hemolysis, jaundice and hyperlipidemia; 2. Pregnant or lactating women; 3. Treatment or diagnosis of any cancer in five years. 4. The subjects had poor compliance and were not willing to receive lung cancer screening. 5. Patients with a history of organ transplantation or long-term use of immunosuppressive agents or people with HIV 6. Suffering from an autoimmune disease. 7. Having a history of surgery within one year (except biopsy); 8. Other situations not appropriate to participate judged by the researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| serum test of autoantibodies;LDCT;SEN, SPE, ACC, AUC of ROC; | — |
Secondary
| Measure | Time frame |
|---|---|
| tumor antigen biomarker; | — |
Countries
China
Contacts
Public ContactZhong Liu
The First Affiliated Hospital, Zhejiang University
Outcome results
None listed