intrauterine adhesions
Conditions
Interventions
MenSCs Group:MenSCs transplantation+Hormone therapy
Hormone Group:Hormone therapy
Sponsors
Shengjing Hospital affiliated to China Medical University
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1) Aged 20-40 years; 2) Hysteroscopic diagnosis of grade III and above (European Endoscopy Association diagnostic criteria) intrauterine adhesions, recurrent intrauterine adhesions or scars; 3) Pre-uterine adhesion lysis or hormone replacement therapy can not restore the intimal regeneration.
Exclusion criteria
Exclusion criteria: 1) Those who cannot accept the treatment observation procedure required by the test; 2) There are contraindications for hysteroscopic surgery; 3) Congenital uterine malformations; 4) Severe adenomyosis; 5) Uterine fibroids that may affect embryo implantation; 6) The investigator judges that there are other uterine factors that are not suitable for embryo implantation; 7) Patients with chromosomal abnormalities; 8) Reproductive system tuberculosis; 9) Chronic wasting or hemorrhagic diseases; 10) Untreated hydrosalpinx; 11) Estrogen Treatment contraindications; 12) Systemic diseases, such as patients with thrombosis, cardiopulmonary disease, hematopoietic diseases and malignant tumors; 13) Patients without fertility requirements.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Live birth rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| endometrial thickness;endometrial morphology;subendometrial zone vascularity;conception rate; | — |
Countries
China
Contacts
Public ContactJichun Tan
Shengjing Hospital affiliated to China Medical University
Outcome results
None listed