Study for the safety and efficacy of hypochlorite eye drops in the treatment of infectious keratitis

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900027108

Enrollment

Unknown

Registered

2019-11-01

Start date

2019-11-01

Completion date

Unknown

Last updated

2019-11-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infectious keratitis

Interventions

Bacterial keratitis routine treatment group: ????? Antibiotic eye drops

Bacterial keratitis combined treatment group:Antibiotics + Hypochlorite Eye Drops

Fungal keratitis routine treatment group:Antifungal drugs

Fungal keratitis combined treatment group:Antifungal Drugs + Hypochlorite Eye Drops

Eligibility

Sex/Gender

All

Age

12 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Infectious keratitis with clear pathogen (bacterial or fungal); 2. Age choice: over 12 years old; 3. Gender selection: no restrictions; 4. The subject or his legal guardian knows and signs the informed consent; 5. No clinical trial participants in the past month. 6. Ulcer lesions exceed the first 1/3 corneal thickness

Exclusion criteria

Exclusion criteria: 1. Uniocular patients; 2. Corneal thickness is less than 300 microns;. 3. Simultaneous scleritis; 4. Can not cooperate with: such as severe cough, hemiplegia, facial paralysis, cerebral palsy, as well as mentally retarded patients, deaf patients. 5. Pregnant or lactating women; 6. Researchers do not consider it appropriate to participate in this clinical trial.

Design outcomes

Primary

Measure	Time frame
Vision;corneal fluorescein staining;Cytological examination;Detection of fungal hyphae;Corneal ulcer depth;	—

Countries

China

Contacts

Public ContactGuo Jianxin

Affiliated Hospital of Xuzhou Medical University

Guojianxin_724@126.com+86 18052268179

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026