Lumbar degeneration disease
Conditions
Interventions
Experiment group A:Preoperative and postoperative use of tranexamic acid
Comparison group A:The same time using a physiological saline
Experiment group B:Use of tranexamic acid preoperative
Comparison group B:Wound topical tranexamic acid used before the end of the surgical
Sponsors
Hefei Orthopaedics Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) in conjunction with patient history, signs and imaging diagnosis clear; 2) conservative treatment for three months inaccurate; 3) patients without the combined liver and kidney dysfunction, no bleeding embolism, no blood system-related diseases; 4) are passing through the transforaminal lumbar interbody fusion (TLIF) surgery; 5) for the first time lumbar surgery; 6) the relevant medical records with complete data; 7) surgery performed by the same group of surgeons.
Exclusion criteria
Exclusion criteria: 1) lumbar revision surgery; 2) Lumbar infection, or lumbar spinal tuberculosis by tumor; 3) diabetes, and perioperative glycemic control; 4) scoliosis, spinal lesions deformity ankylosing spondylitis; 5) intraoperative cerebrospinal fluid leakage.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Haemoglobin;Hematocrit;Intraoperative dominant blood loss;Postoperative dominant blood loss; | — |
Countries
China
Contacts
Public ContactRui Zhang
Hefei Orthopaedics Hospital
Outcome results
None listed