To investigate biomarkers of the relationship between maternal intrauterine infection and neonatal adverse outcomes: an observational study

Biomarkers for perinatal inflammation: an observational study

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR1900027082

Enrollment

Unknown

Registered

2019-10-31

Start date

2019-11-01

Completion date

Unknown

Last updated

2019-11-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chorioamnionitis

Interventions

gestational age < 32 weeks with chorioamnionitis:N/A

gestational age 32-37 weeks without chorioamnionitis:N/A

gestational age 32-37 weeks with chorioamnionitis:N/A

Eligibility

Sex/Gender

Female

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. The mother is admitted and her infant is born at the participating departments of Gynaecology and Obstetrics. 2. The newborn infant is admitted at the participating neonatal department. 3. Gestational age at delivery < 37 weeks. 4. Parenteral consent is signed by at least a parent agreeing that amniotic fluid, cord blood, placenta, meconium, neonatal blood and faeces will be collected.

Exclusion criteria

Exclusion criteria: 1. Major congenital abnormalities or birth defects; 2. Life expectancy < 24 hours.

Design outcomes

Primary

Measure	Time frame
Markers in amniotic fluid, cord blood and meconium associated with chorioamnionitis;	—

Secondary

Measure	Time frame
Markers in amniotic fluid, cord blood and meconium associated with gestational age at delivery;Markers in placenta associated with EOS;	—

Countries

China

Contacts

Public ContactPingping Jiang

School of Public Health, Sun Yat-Sen University

jiangpp3@mail.sysu.edu.cn+86 13266595242

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026