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novel biomarkers for diagnosis and treatment of diabetic cardiomyopathy

novel biomarkers for diagnosis and treatment of diabetic cardiomyopathy

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900027080
Enrollment
Unknown
Registered
2019-10-30
Start date
2020-01-01
Completion date
Unknown
Last updated
2019-11-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

diabetic cardiomyopathy

Interventions

FGF1,&#32
FGF2,&#32
FGF21,&#32
FGF23,&#32
TNFa,&#32
IL-1b,&#32
MCP-1,&#32
ICAM-1,&#32
VCAM-1,&#32
GLUT4 Acetyl-COA,&#32
b-oxidation,&#32
PPARg,&#32
PPARb,&#32
PPARa,&#32
Col1a1,&#32
col3a1,&#32

Sponsors

Changzhou First People's Hospital (The Third Affiliated Hospital of Soochow University)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
35 Years to 70 Years

Inclusion criteria

Inclusion criteria: The patients were hospitalized with T2DM in the Endocrinology Department of the Third Affiliated Hospital of Soochow University from April 2020 to June 2025, regardless of the duration of diabetes. The medical treatment consisted of oral anti-hyperglycemic agents and/or insulin therapy.

Exclusion criteria

Exclusion criteria: 1. A history of coronary artery disease, hypertension, valvular heart disease, or other type of cardiovascular disease; 2. A self-reported history of symptomatic micro- or macrovascular complications of diabetes (including nephropathy, neuropathy, retinopathy, peripheral vascular disease, and stroke); 3. Pregnancy; 4. Other significant comorbidities including malignancy, renal failure, thyroid dysfunction, or significant psychiatric illness.

Design outcomes

Primary

MeasureTime frame
Cardiac ultrasound and ECT;SPE, SEN, ACC, AUC of ROC;

Countries

China

Contacts

Public ContactLichan Tao

Changzhou First People's Hospital (The Third Hospital of Soochow University)

sherry0019@126.com+86 13775021255

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 26, 2026