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Effect of ropivacaine on magnesium sulfate combined with ultrasound-guided quadratus lumborum blocks on postoperative analgesia in gynecological laparoscopic surgery

Effect of ropivacaine on magnesium sulfate combined with ultrasound-guided quadratus lumborum blocks on postoperative analgesia in gynecological laparoscopic surgery

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900027066
Enrollment
Unknown
Registered
2019-10-30
Start date
2019-12-01
Completion date
Unknown
Last updated
2019-11-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative analgesia

Interventions

Ropivacaine group:The posterior edge of quadratus psoas on each side was injected with 0.375% ropivacaine 20ml and 2ml normal saline
Magnesium sulfate group:The posterior edge of quadratus psoas on each side was injected with 0.375% ropivacaine 20ml and 2ml 10% Magnesium sulfate
control group:The posterior edge of quadratus psoas on each side was injected with 22ml normal saline

Sponsors

Shengjing Hospital Affiliated to China Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
40 Years to 60 Years

Inclusion criteria

Inclusion criteria: From December 20189to June 2020, 90 patients with ASA I or II who were selected to receive total hysterectomy or total hysterectomy + adnexectomy in our hospital, aged 40 ~ 60 years old, weighing 45 ~ 75kg.

Exclusion criteria

Exclusion criteria: Preoperative BMI > 32 kg/m2; Hypersensitivity to ropivacaine, long-term use of calcium channel blockers, recent use of antipsychotic drugs, alcohol or drug abuse; Puncture site infection, abnormal coagulation function, previous abdominal surgery, peripheral neuropathy; Mental and intellectual disabilities, language communication disorders.

Design outcomes

Primary

MeasureTime frame
Visual Analogue Scale;time and times of analgesia pump press ;

Secondary

MeasureTime frame
postoperative analgesia satisfaction;

Countries

China

Contacts

Public ContactZhao Xiaochun

Shengjing Hospital Affiliated to China Medical University

xiaochunzhao119@163.com+86 18940257646

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 13, 2026