Onychomycosis
Conditions
Interventions
Group 1:chemical avulsion for one time
Group 2:chemical avulsion for twice
Group 3:chemical avulsion combination with mechanical nail abrasion
Group 4:chemical avulsion combination with oral ITC
Group 5:oral ITC
Sponsors
Shanghai Dermatology Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Patients with onychomycosis confiremed by history, clinical manifestations and laboratory results; (2) Fungal direct microscopy was positive and (or) fungal culture was positive; (3) Aged 18-65 years old male or female; (4) Women of childbearing age take effective contraceptive measures during the study period.
Exclusion criteria
Exclusion criteria: (1) Local combination of paronychia, severe bacterial infection or other skin diseases which may interfere with the diagnosis and treatment; (2) Patients with serious heart, liver, kidney disease, patients with diabetes and mental diseases; (3) Systemic use of glucocorticoid or immunosuppressant within 3 months; (4) Systemic use of antifungals within 6 months or topical use of antifungals within 1 month; (5) Pregnant and breast-feeding women; (6) Continuous or semi-continuous nail discoloration.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| clinical efficacy rate; | — |
Countries
China
Contacts
Public ContactCai Qing
Shanghai Dermatology Hospital
Outcome results
None listed