AIDS-related lymphoma
Conditions
Interventions
ARL group:NA
Control group(Non-ARL HIV carrier):NA
Sponsors
Shanghai Public Health Clinical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Diagnosed to be HIV carrier when aquiring serum, lymph tissue or lymphoma tissue sample; 2) For ARL group: Pathologically diagnosed ARL patients (including Burkitt lymphoma, Diffuse large B-cell lymphoma, Plasma blastoma and Primary effusion lymphoma), tissue of lymphoma and tumor-free lymph will be collected as sample.(About 60 cases) For Control group: Pathologically diagnosed non-ARL patient.(About 20 cases); 3) Patient never accept radiotherapy or chemotherapy; 4) Patient signed informed consent form.
Exclusion criteria
Exclusion criteria: 1) Previous history of malignant cancer; 2) Patient with cardiovascular and cerebrovascular diseases.(Cerebral stroke, Myocardial infarction etc); 3) Patient with serious hepatic and/or renal disfunction; 4) Attended other clinical trial 3 months before sampling in this project; 5) Female patient in preganacy or lactation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HIV-1S75X in serum;Wild type HIV-1p17 in serum;S75X in lymphoma and lymph gland sample;p17 in lymphoma and lymph gland sample;p24 in lymphoma and lymph gland sample;Nef in lymphoma and lymph gland sample;Tat in lymphoma and lymph gland sample;gp120 in lymphoma and lymph gland sample;EBV coded RNA;p53 in lymphoma and lymph gland sample;Ki-67 in lymphoma and lymph gland sample;CD34 in lymphoma and lymph gland sample;D2-40 in lymphoma and lymph gland sample; | — |
Countries
China
Contacts
Public ContactFeng Yanling
Shanghai Public Health Clinical Center
Outcome results
None listed