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Study for the effect of constraint- induced movement therapy training on upper extremity dysfunction

Study for the effect of constraint- induced movement therapy training on upper extremity dysfunction

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900027032
Enrollment
Unknown
Registered
2019-10-29
Start date
2020-01-01
Completion date
Unknown
Last updated
2019-11-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stroke

Interventions

Experimental group:constraint- induced movement therapy
control group:routine rehabilitation treatment

Sponsors

Huashan Hospital North, Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. age 30-75; 2. it is in accordance with the diagnostic standard of "stroke" set by the fourth national conference of cerebrovascular diseases, and the diagnosis is clear by CT or MRI, the course of disease is more than 2 weeks, and the vital signs are stable within 6 months. 3. unilateral lesions, located in the basal nucleus of the internal capsule, involving white matter but not gray matter; 4. the wrist on the affected side should be able to extend back actively at least 10 degree and the other two fingers, except the thumb, should extend back at least 10 degree; 5. the Ashworth grade of the affected upper limb was <=1 +; 6. able to walk independently with sufficient balance force; 7. no cognitive impairment, able to cooperate with treatment and evaluation; 8. willing to follow the guidance and have good desire for rehabilitation and good family support; 9. are willing to sign the informed consent; 10. willing to perform DTI before and after treatment.

Exclusion criteria

Exclusion criteria: 1. patients with severe cardiopulmonary, hepatorenal insufficiency are not suitable for rehabilitation training; 2. combined with malignant tumor; 3. patients with severe cognitive impairment (MMSE < 22 points), who could not cooperate with the training; 4. uncontrolled hypertension, blood pressure higher than 180 / 100mmhg; 5. deaf and mute; 6. unable to receive treatment in designated hospital for a long time; 7. participants in other clinical studies at the same time; 8. pregnancy; 9. other organic diseases such as intracranial tumor.

Design outcomes

Primary

MeasureTime frame
Action Research Arm Test;

Secondary

MeasureTime frame
Fugl-Meyer;

Countries

China

Contacts

Public ContactWang Yuyuan

Huashan Hospital North, Fudan University

wangyuyuan1220@163.com+86 13818915325

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026