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Fusidic acid minimized risks of inflammation and postinflammatory hyperpigmentation after ablative fractional CO2 laser resurfacing in Chinese patients: a randomized, controlled trial

A multi-center, randomized, controlled clinical trial of fusidic acid ointment to prevent infection and post-inflammatory hyperpigmentation after laser surgery

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900027000
Enrollment
Unknown
Registered
2019-10-28
Start date
2018-08-30
Completion date
Unknown
Last updated
2019-11-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acne scar ablative CO2 laser postoperative

Interventions

Experimental group:Fusidic acid
Control group:Erythromycin

Sponsors

Plastic Surgery hospital, Peking Union Medical College and Chinese Academy of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. Willing to participate in this trial, can adhere to medication, prohibit combined medication and timely follow-up; 2. aged 16~70 years old male and female; 3. Patients with facial and neck acne scars treated with carbon dioxide laser or holmium laser.

Exclusion criteria

Exclusion criteria: 1. Had been participated in other clinical trial within 4 weeks before the start of the study; 2. The subjects who have been treated with dot laser treatment, have a history of sun exposure or a history of photosensitizing drugs; 3. Fusidic acid, erythromycin drugs, allergic to any of its preparations; 4. Pregnant or lactating women, have obvious endocrine system diseases, mental illness, blood diseases, liver and kidney disease, patients with cardiovascular and cerebrovascular diseases, immune dysfunction and bleeding tendency; 5. suffering from other facial skin diseases may interfere with the efficacy of the judgment: such as solar dermatitis, facial psoriasis, facial seborrheic dermatitis, facial eczema, etc.; 5. Need to combine system use or facial antibiotics, corticosteroids, retinoids, etc.

Design outcomes

Primary

MeasureTime frame
acne scar;

Countries

China

Contacts

Public ContactBaoxi Wang

Plastic Surgery hospital, Peking Union Medical College and Chinese Academy of Medical Sciences

674280016@qq.com+86 18710068165

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026