breast cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Breast surgery patients undergoing elective modified radical mastectomy in department of breast cancer; 2. Aged greater than or equal to 18 years; 3. ASA I-II level; 4. Normal communication; 5. Volunteer to participate in clinical trial and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Severe respiratory and circulatory system diseases: such as severe coronary heart disease, chronic obstructive pulmonary disease, etc.; 2. Endocrine system diseases: such as pituitary tumors, severe diabetes, cortisol hyperplasia, pheochromocytoma, etc.; 3. Mental and psychological diseases: such as schizophrenia, depression, history of taking chronic analgesics and opioid dependence; 4. History of bleeding diseases or coagulation dysfunction; 5. Excluding patients with concomitant infectious diseases and abnormal preoperative inflammatory indicators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain VAS score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood pressure;Heart rate;Pulse oxygen saturation;Serum adrenalin;Serum norepinephrine;Serum cortisol;Intraoperative anesthetic dosage;Postoperative complications;Operation time;Anesthesia time; | — |
Countries
China
Contacts
Department of Anesthesiology, the First Affiliated Hospital of Anhui Medical University