Infant intestinal health
Conditions
Interventions
Experimental group:Take 1 bag, 2g/bag, 1x10^10cfu/g of bacterial powder containing Lactobacillus paracasei N1115 every day
take it with boiled water or milk at a temperature of no more than 40 degree C
the intervention time is 12 weeks.
Control group:Take 1 bag of placebo (mainly the excipient maltodextrin of Lactobacillus paracasei) in the same package every day, and take the same method for 12 weeks.
Sponsors
Peking University
Eligibility
Sex/Gender
All
Age
No minimum to 2 Years
Inclusion criteria
Inclusion criteria: 1. ceasarean-born infants; 2. aged 6-24 months infants meeting the standard for healthy infants of their age group.
Exclusion criteria
Exclusion criteria: 1) subjects that have been taken prebiotics or probiotics 2 weeks before the beginning of the experiment or do not want to be stopped; 2) subjects with serious acute or chronic diseases (cardiovascular diseases, gastrointestinal diseases, endocrine diseases, immune system diseases, metabolic diseases or diseases that the researchers think are not suitable for the study); 3) subjects that are taking some drugs that are treated or taken are considered to interfere with the purpose of the study, increase the risk of the study or lead to the problem that the results of the study cannot be explained; 4) subjects that have a history of taking antibiotics in the past 3 months; 5) subjects do not accept the arrangement of random subjects; 6) subjects participate in other studies less than 60 days before this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| stool consistency;intestinal microflora; | — |
Secondary
| Measure | Time frame |
|---|---|
| salivary cortisol;Faecal short chain fatty acids;Fecal slgA; | — |
Countries
China
Contacts
Public ContactZhang Yumei
Peking University Health Science Center
Outcome results
None listed