CHD
Conditions
Interventions
Index test:CoronaryScope 
CT 
Flow 
Reserve
Sponsors
FUWAI HOSPITAL,CAMS&PUMC
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 80 years; 2. Able to provide signed informed consent; 3. Patients have at least one suspected stenosis of coronary artery and are planning to undergo PCI surgery. CCTA inclusion criteria: 1. 64-detector row CT scanners or higher; 2. CCTA image should have a high quality and can visualize stenosis in a clear way; 3. At least one stenosis with diameter stenosis of 30%-90% by visual estimate; 4. Reference vessel size > 2 mm in stenotic segment by visual estimate.
Exclusion criteria
Exclusion criteria: General Exclusion Criteria: 1. pregnant or breastfeeding women or on planning; 2. acute myocardial infarction occurs in 30 days ahead of CCTA scan; 3. patients who underwent CABG, PCI, ICD or TAVI surgeries before; 4. Allergy to contrast agent or adenosine; 5. Hypertrophic obstructive cardiomyopathy or Severe heart failure (NYHA>=III); 6. BMI>35kg/m2; 7. S-creatinine>178umol/L; 8. Ineligible for diagnostic intervention or FFR examination. CCTA exclusion criteria: 1. Poor angiographic image quality precluding contour detection; 2. Chronic Total Occlusion of target vessel; 3. The interrogated stenosis is caused by aneurysm or myocardial bridge; CAG exclusion criteria: 1. Severe tortuosity of target vessel.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fractional Flow Reserve Result of surgical examination;SEN, SPE, ACC, AUC of ROC; | — |
Countries
China
Contacts
Public ContactYida Tang
Fuwai Hospital, Chinese Academy of Medical Sciences
Outcome results
None listed