Transanal specimen extraction in totally laparoscopic colorectal cancer surgery ------ a prospective randomized controlled clinical study

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900026970

Enrollment

Unknown

Registered

2019-10-27

Start date

2019-10-31

Completion date

Unknown

Last updated

2019-10-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal Cancer

Interventions

NOSES Group:Transanal specimen extraction

Control group:Conventional laparoscopy

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. aged 18 Years to 75 Years; 2. pathological proved CRC adenocarcinoma by endoscopic biopsy; 3. located in rectum or sigmoid colon; 4. preoperative clinical T1-3NxM0; 5. the diameter of tumor is less than 5cm or the extent of invasion less than 1/2 circle of bowel wall if tumor located in low rectum; 6. BMI <=34kg/m2; 7. Patient able to understand and sign written informed consent.

Exclusion criteria

Exclusion criteria: 1. Other malignant tumors history; 2. Multiple colorectal cancer; 3. Patients are to be received the abdominal perineal resection; 4. local resection; 5. There are contraindications for laparoscopic surgery; 6. Repeated abdominal pelvic surgery or extensive abdominal adhesions; 7. Complications need emergency surgery (occlusion, sub-occlusion, massive hemorrhage and abscesses); 8. Colorectal tumor extension towards abdominal wall and/or adjacent organ making liver R0 resection impossible immediately; 9. FAP or Lynch syndrome or patients with active inflammatory bowel disease; 10. American Society of Anesthesiologists (ASA) grading >=IV and/or, Eastern Cooperative Oncology Group(ECOG) score >= 2 11. Patients with severe liver and kidney function, cardiopulmonary function, coagulopathy or a serious underlying disease that cannot tolerate surgery; 12. Physical or psychological dependence; 13. Pregnant or breast feeding women; 14. Not controlled pre-operational infection; 15. Other clinical or laboratorial condition not recommended by investigators; 16. Previous anal disease caused by anal dysfunction or anal stenosis.

Design outcomes

Primary

Measure	Time frame
3-year local recurrence rate;	—

Countries

China

Contacts

Public ContactXishan Wang

Cancer Hospital, Chinese Academy of Medical Sciences

wxshan1208@126.com+86 13552367779

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026