Early esophageal carcinoma and precancerous lesions
Conditions
Interventions
Group B (dental floss traction group):denta floss traction
Group C (endoloops traction group):endoloops traction
Group A:traditional ESD surgical method
Sponsors
Zhengzhou University First Affiliated Hospital
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: (1) Before preoperative endoscopic biopsy in January, the pathology was diagnosed as preesophageal carcinoma or early carcinoma: Epithelial(HGIN) or moderate or severe atypical hyperplasia; (2) Preoperative use of white light, iodine staining, enlarged endoscopic narrowband imaging(NBI-ME), endoscopy ultrasound (EUS) and chest CT examination suggested that the lesions were limited to M1, M2, M3 or sm1 and there was no vascular and lymphatic metastasis; (3) The length of the lesion >= 2cm.
Exclusion criteria
Exclusion criteria: (1) There has been lymph node metastasis or distant metastasis; (2) The tumor has invaded the inherent muscle layer; (3) At the same time suffering from serious diseases such as heart, lungs, kidneys, brain, blood and other important organs; (4) There is a serious bleeding tendency (prothrombin time > 14 S or platelet count < 90 x10^9/L. Because cardiovascular and other diseases require long-term anticoagulant drugs, even if the coagulation function is in the normal range before surgery, at least 3 to 7D of the drug should be stopped, and 3 to 7D should be stopped after surgery). (5) Iodine allergy. (6) Negative mucosal lifting. (7) Those who refuse to undergo endoscopic treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total time of ESD surgery;ESD operation time;Disease stripping time;Area of diseased tissue; | — |
Secondary
| Measure | Time frame |
|---|---|
| Total number and time of installation of ancillary equipment;Total and Number of Submucosal Supplements;Traction equipment related complications;Traction equipment related complications;Number of perforations and uncontrolled bleeding during surgery, and the circumstances;Number of sites damaged in deep tissue(different depths) during operation;Number of postoperative complications and their specific situation; | — |
Countries
China
Contacts
Public ContactLiu Bingrong
The First Affiliated Hospital of Zhengzhou University
Outcome results
None listed