lung cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. aged 45-70 years old; 2. ASA was classified as I-III; 3. patients who underwent thoracoscopic radical resection of lung cancer.
Exclusion criteria
Exclusion criteria: 1. It is impossible to judge whether the lung cancer is primary because of the previous history of other malignant tumors; 2. Before the operation, radiotherapy, chemotherapy, anti-inflammatory drugs, analgesics and hormone drugs were used; 3. Metastasis of other organs; 4. Those who are allergic to local anesthetics; 5. The patients with abnormal liver function were defined as (total bilirubin=2mg / dl). 6. Patients with abnormal renal function (defined as glomerular filtration rate<60ml/min/1.73m2); 7. Sinus bradycardia, more than two degrees of atrioventricular block; 8. Chronic pain; 9. Mental illness and communication disorder; 10. Refusing to accept the systemic lidocaine;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| QoR-40 scores; | — |
Secondary
| Measure | Time frame |
|---|---|
| Ppeak;Ppeak;Qs/Qt;PA-aO2;OI;Complications such as respiratory failure, atelectasis, pulmonary infection and ARDS occurred within 7 days after operation;The use of opioids in perioperative period and the consumption of remedial analgesics (including NSAIDs) within 24 hours after operation;The recovery time of gastrointestinal function after operation, including the time of first exhaust, defecation and eating, and the time of first getting out of bed after operation; | — |
Countries
China
Contacts
Affiliated Hospital of Xuzhou Medical University