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Analysis of CYP2C19 gene polymorphism and curative effect of HP eradication in children and related factors: a medical records based study

Analysis of CYP2C19 gene polymorphism and curative effect of HP eradication in children and related factors: a medical records based study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900026867
Enrollment
Unknown
Registered
2019-10-24
Start date
2016-09-01
Completion date
Unknown
Last updated
2019-10-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Helicobacter pylori infection in children

Interventions

HomEM/HetEM/PM:Nil

Sponsors

The Affiliated Children's Hospital of Zhejiang University Medical College
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) children admitted to children's hospital of zhejiang university medical college from September 2016 to December 2018 due to digestive tract discomfort such as "abdominal pain, abdominal distension, regurgitation, belching, nausea, vomiting, heartburn, chest pain, hematemesis, black stool"; (2) gastroscopy and positive urease test (RUT); (3) after 2 weeks of normal anti-hp eradication treatment, and 1 month later, carbon 13 breath test results can be used to determine the efficacy; (4) culture of HP in gastric antrum mucosa before treatment.

Exclusion criteria

Exclusion criteria: (1) serious impairment of heart, liver and renal function; (2) non-formal treatment or inadequate course of treatment or other reasons for halfway out.

Design outcomes

Primary

MeasureTime frame
CYP2C19;—

Contacts

Public ContactJiang Mizu
mizu@zju.edu.cn+86 13857107171

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026