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Combining mind body physical exercise, cognitive training, and nurse-led risk factor modification to enhance cognition among older adults with mild cognitive impairment: a randomized controlled trial

Combining mind body physical exercise, cognitive training, and nurse-led risk factor modification to enhance cognition among older adults with mild cognitive impairment: a randomized controlled trial

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900026857
Enrollment
Unknown
Registered
2019-10-24
Start date
2019-11-01
Completion date
Unknown
Last updated
2023-11-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

mild cognitive impairment

Interventions

Sponsors

JC School of Public Health and Primary Care, The Chinese University of Hong Kong
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) aged between 60 years and 80 years; (2) having Montreal Cognitive Assessment Hong Kong version (HK-MoCA) score within 19-25 after adjusting for years of educational (+1 point if < 6 years) suggesting MCI according to published research; (3) being physically stable, as assessed by the study physician.

Exclusion criteria

Exclusion criteria: (2) concurrent treatment with structured cognitive training, regular physical exercises including Tai Chi or other lifestyle modifications (e.g., diet) although no restrictions will be imposed on leisure activity; (3) a past history of bipolar affective disorder or psychosis; (4) one or more significant communicative impairments. The use of psychotropic medication; this does NOT constitute an exclusion criterion, but any use of anti-dementia and other psychotropic medications should be kept on a stable dosage for at least three months before enrolment and also throughout the study.

Design outcomes

Primary

MeasureTime frame
The Chinese version of the Alzheimer's Disease Assessment Scale - cognitive subscale (ADAS-Cog);

Secondary

MeasureTime frame
CDR sum of box;The Disability Assessment for Dementia (DAD);Quality of life (EQ5D);Depression and anxiety;Cigarette smoking, alcohol drinking, diet and physical exercise;Health service utilization;Common diseases;

Countries

China

Contacts

Public ContactProf. Samuel Yeung Shan WONG

JC School of Public Health and Primary Care, The Chinese University of Hong Kong

yeungshanwong@cuhk.edu.hk+852 2252 8774

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026