Infertility
Conditions
Interventions
Sponsors
Shandong Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
Female
Age
23 Years to 37 Years
Inclusion criteria
Inclusion criteria: 1. Aged 23-37 years, junior high school education level or above, in line with the diagnosis of infertility. 2. IVF/ICSI assisted pregnancy due to female fallopian tube factors or male factors, using luteal short-term and long-term regimens. 3. Ensure that the patient is free of uterine structural disorders, systemic diseases and external ear health, that the patient has not recently been diagnosed with anxiety disorder, or that he has not received any anxiety treatment before. 4. Informed consent, volunteer.
Exclusion criteria
Exclusion criteria: 1. Complicated with immune diseases, infectious diseases, severe heart diseases and chronic wasting diseases; endometriosis; chromosome abnormalities; polycystic ovary syndrome. 2. Previous history of ovarian surgery, previous history of radiotherapy and chemotherapy, hysteroscopy showed weak uterine lesions, mania, depression, or schizophrenia accompanied by anxiety. 3. The patients with mental depression caused by hyperthyroidism, hypertension, coronary heart disease, drug dependence or other mental nerve diseases were excluded. Those who have serious adverse events in the course of research and treatment and are not suitable to continue to participate in the experiment are excluded. 4. To eliminate the withdrawal response of excitatory drug overdose, hypnotic sedative or anti-anxiety drugs, and to eliminate obsessive-compulsive disorder, fear, hypochondria, dysmenorrhea, mania and depression. Or schizophrenia and other concomitant anxiety.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Levels of norepinephrine, cortisol, IL-6, IL-1 ß, tumor necrosis factor a (TNF- a) and neuropeptide Y in follicular fluid and serum;Clinical indicators of IVF (total use of Gn, days of Gn use, egg recovery rate, fertilization rate, cleavage rate, high quality embryo rate, clinical pregnancy rate); | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of pregnancies, education, address, occupation, infertility years, scale scores; | — |
Countries
China
Contacts
Public ContactSun Zhengao
Shandong Provincial Traditional Chinese Medicine Reproductive Center
Outcome results
None listed