stroke
Conditions
Interventions
Experimental group:repetitive transcranial magnetic stimulation,rTMS
Control group:task-oriented training, TOT
Sponsors
The Second Affiliated Hospital of Xi'an Jiaotong University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) first-ever stroke meeting the criteria of World Health Organization and the 5th national conference on cerebrovascular diseases in 2014, and confirmed by clinical neuroimaging (CT/MRI); (2) 1-12 months post stroke; (3) stable medical condition; (4) aged 18-85 years; (5) upper extremity motor impairment; (6) normal cardiopulmonary function, and stable vital signs; (7) commitment to follow the rules, and good cooperation in the study; (8) healthy lifestyle during the research; (9) some residual arm motor activity as defined by Brunnstrom recovery stages >= III; (10) able to provide informed consent.
Exclusion criteria
Exclusion criteria: (1) current consciousness disorders, psychosis, cognitive dysfunction, or mix aphasia limiting the ability to comply with evaluation and treatment regimen; (2) hypertonia with Ashworth scales >= III or manual muscle testing grade <= 2; (3) unstable cardiac, liver or renal diseases; (4) severe pain in the affected arm; (5) severe limitation of shoulder or elbow joint range of motion; (6) history of seizures; (7) severe orthopedic impairments in the affected arm; (8) unstable fracture or severe osteoporosis; (9) cardiac pacemaker or implanted device or metal in the brain; (10) severe disabilities prior to stroke (modified Rankin Scale, mRS = 5); (11) severe visual or auditory disorders; (12) pregnancy or lactation; (13) skull missing; (14) participation in concurrent clinical trial; (15) other diseases interferring with participants in the experiment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Wolf Motor Function Test, WMFT; | — |
Secondary
| Measure | Time frame |
|---|---|
| the Upper Extremity Section of the Fugl-Meyer Assessment, FMA-UE;the Upper Extremity Section of the Modified Ashworth Scale, MASUE;Modified Barthe Index, MBI;Stroke-specific Quality of Life scale, SS-QOL;Motion Evoked Potential, MEP; | — |
Countries
China
Contacts
Public ContactQiaojun Zhang
The Second Affiliated Hospital of Xi'an Jiaotong University
Outcome results
None listed