Polycystic ovary syndrome
Conditions
Interventions
control group:NA
Sponsors
Luoyang Central Hospital Affiliated to Zhengzhou University
Eligibility
Sex/Gender
Female
Age
21 Years to 35 Years
Inclusion criteria
Inclusion criteria: The diagnosis of PCOS was accorded with the 2003 Rotterdam diagnostic criteria. All enrolled patients must abide to at least two items in the following criteria: 1. infrequent ovulation and/or anovulation; 2. with clinical features of hyperandrogenism or hyperandrogenemia; 3. ultrasonic testing within 3 - 5 days after the withdrawal of menstrual cycle and progesterone displayed that the number of small follicles in unilateral or bilateral ovary with a diameter of 2 – 9 mm was in fact more than 12 mm. Meanwhile, normal ovarian tissues were gathered from 28 healthy women in childbearing age (age < 35 years) with regular menstrual cycle and no diagnosis of PCOS. They underwent gynecological operation in follicular phase and this histopathologically confirmed no obvious, abnormal morphology.
Exclusion criteria
Exclusion criteria: Patients who had been administered with any hormone such as contraceptives, antiandrogens, and insulin sensitizers, that are more prone to interfering with secretions and metabolism of sex hormones.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| miR-199a-5p mRNA expression; | — |
Countries
China
Contacts
Public ContactFang Wang
Luoyang Central Hospital Affiliated to Zhengzhou University
Outcome results
None listed