Skip to content

Study for thrombophilia and its treatment in IVF-ET

Study for thrombophilia and its treatment in IVF-ET

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900026806
Enrollment
Unknown
Registered
2019-10-23
Start date
2019-10-24
Completion date
Unknown
Last updated
2019-10-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thrombophilia

Interventions

Intervention group1:LDA
Intervention group2:LMWH

Sponsors

Beijing Obstetrics and Gynecology Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
No minimum to 40 Years

Inclusion criteria

Inclusion criteria: (1) Aged <40 years; (2) There were no abnormalities in blood routine coagulation and thrombophilia exam before IVF-ET treatment; (3) Fresh cycle; (4) Number of platelets , D-Dimer is elevated after IVF-ET treatment.

Exclusion criteria

Exclusion criteria: (1) There is a clear family history of arteriovenous thromboembolic disease; (2) a history of arteriovenous thromboembolism; (3) recurrent spontaneous abortion >= 3 times; (4) repeated implantation failure >= 3 times; (5) have chronic wasting diseases such as diabetes and nephropathy; (6) have immune diseases such as anticardiolipin syndrome, systemic lupus erythematosus, idiopathic thrombocytopenia, and immune nephropathy; (7) have a history of surgery in the past six months; (8) history of gastroduodenal ulcer; (9) coagulation index Fib significantly decreased, PT, APTT significantly prolonged, suffering from severe coagulopathy, active bleeding; (10) D-Dimer > 5 mg / L during IVF-ET treatment, or vascular ultrasound suggest the presence of thrombosis.

Design outcomes

Primary

MeasureTime frame
Coagulation index;

Secondary

MeasureTime frame
Clinical pregnancy rate;Embryo implantation rate;Abortion rate;

Countries

China

Contacts

Public ContactChanwei Jia

Beijing Obstetrics and Gynecology Hospital, Capital Medical University

jiachanwei@163.com+86 13520418189

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026