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A multicenter randomized controlled trial for Wen-Jing Hua-Yu Tong-Luo Decoction in relieving chemotherapy induced peripheral neuropathy (CIPN)

A multicenter randomized controlled trial for Wen-Jing Hua-Yu Tong-Luo Decoction in relieving chemotherapy induced peripheral neuropathy (CIPN)

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900026763
Enrollment
Unknown
Registered
2019-10-21
Start date
2019-11-01
Completion date
Unknown
Last updated
2019-10-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chemotherapy induced peripheral neuropathy(CIPN)

Interventions

Sponsors

Longhua Hospital Affiliated to Shanghai University of traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) patients with numbness of hands and feet after chemotherapy were diagnosed as peripheral neuropathy; (2) chemotherapy patients with definite diagnosis of cytology or pathology; (3) patients aged 18 to 80 years; (4) KPS (Karnofsky's speech status) score is more than 50; (5) estimated survival time >=6 months; (6) normal blood picture, renal function, liver function and various biochemical indexes; (7) the patient has good compliance, understands and agrees to accept the treatment, and signs the informed consent.

Exclusion criteria

Exclusion criteria: 1. patients with original nervous system diseases; 2. diabetic patients who may cause peripheral sensory abnormality; 3. patients undergoing other drugs or radiotherapy that may cause peripheral neurotoxicity; 4. mental patients with cognitive loss or mental disorder; 5. patients with severe primary diseases of cardiovascular, cerebrovascular, liver, kidney and hematopoietic system; 6. women who are breastfeeding, pregnant or preparing for pregnancy; 7. people with allergic constitution and multiple drug allergy.

Design outcomes

Primary

MeasureTime frame
Grading of peripheral neuropathy;

Contacts

Public ContactXU Zhenye

Longhua Hospital Affiliated to Shanghai University of traditional Chinese Medicine

xuzhenye1947@126.com+86 15921341313

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026