chemotherapy induced peripheral neuropathy(CIPN)
Conditions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) patients with numbness of hands and feet after chemotherapy were diagnosed as peripheral neuropathy; (2) chemotherapy patients with definite diagnosis of cytology or pathology; (3) patients aged 18 to 80 years; (4) KPS (Karnofsky's speech status) score is more than 50; (5) estimated survival time >=6 months; (6) normal blood picture, renal function, liver function and various biochemical indexes; (7) the patient has good compliance, understands and agrees to accept the treatment, and signs the informed consent.
Exclusion criteria
Exclusion criteria: 1. patients with original nervous system diseases; 2. diabetic patients who may cause peripheral sensory abnormality; 3. patients undergoing other drugs or radiotherapy that may cause peripheral neurotoxicity; 4. mental patients with cognitive loss or mental disorder; 5. patients with severe primary diseases of cardiovascular, cerebrovascular, liver, kidney and hematopoietic system; 6. women who are breastfeeding, pregnant or preparing for pregnancy; 7. people with allergic constitution and multiple drug allergy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Grading of peripheral neuropathy; | — |
Contacts
Longhua Hospital Affiliated to Shanghai University of traditional Chinese Medicine