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Jiawei Peony-Glycyrrhiza Decoction in the treatment of antipsychotic-induced hyperprolactinemia: an observational study

Jiawei Peony-Glycyrrhiza Decoction in the treatment of antipsychotic-induced hyperprolactinemia: an observational study

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900026759
Enrollment
Unknown
Registered
2019-10-21
Start date
2019-11-01
Completion date
Unknown
Last updated
2019-10-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hyperprolactinemia

Interventions

single arm:Chinese Traditional Medicine+Antipsychotic Drugs

Sponsors

Beijing Anding Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. Female patients aged from 18 to 45 years; 2. Had a primary diagnosis of schizophrenia based on International Classification of Diseases, 10th Edition; 3. Were under stable antiphychotic drug treatment; 4. Current conditions were stable, with a score of less than 60 on the Positive and Negative Syndrome Scale(PANSS); 5. Can communicate with the research people and made the consent; 6. Serum PRL levels > 24ng/ml; 7. Had experienced oligomengorrhea and /or amenorrhea or at least one syndrome of hyperprolactinemia.

Exclusion criteria

Exclusion criteria: 1. With unstable physical diseases; 2. Have had suicide and aggression; 3. With alcohol abuse in past a year; 4. With substance abuse in past a year; 5. Be receiving TCM treatment; 6. Be allergied to Traditional Chinese Medicine; 7. Non-drug origin hyperprolactinemia; 8. Obese(BMI>=25)and suffered from severe gynecological disease; 9. During pregnancy or age of sucking or refuse to contraception during the study period.

Design outcomes

Primary

MeasureTime frame
Prolactine;

Countries

China

Contacts

Public ContactXianbin Li

Beijing Anding Hospital

xianbinlili@163.com+86 15801197661

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026