discogenic low back pain
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Chronic low back pain is accompanied by more than two clinical manifestations: sedentary pain, back stretching pain, and difficulty in relieving or maintaining the same posture; 2. Skeletally mature patients with chronic (>=6 months) isolated lumbar back pain, who had not responded to at least 6 months of nonoperative management; 3. MRI evidence of intervertebral disc degeneration.with or without annular tear; 4. Complete medical record; 5. Volunteer to participate in the trial, and signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. Previous lumbar spine surgery; 2. Symptomatic spinal stenosis; 3. Metabolic bone disease, spine fragility fracture history, or trauma/compression fracture,or spinal cancerSpine infection, active systemic infection, bleeding diathesis; 4. Cardiovascular diseases such as cardiovascular and digestive system and other serious diseases; 5. Pregnant and lactating women; 6. Liver and kidney dysfunction; 7. Other autoimmune diseases, allergic diseases and acute and chronic infections; 8. Chronic skin disease or operation area with skin ulcer wound scar; 9. The researchers did not think it would be appropriate to participate in this clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS scoring (visual analogue scoring system); | — |
Countries
China
Contacts
Department of Orthopedics, The Third Affiliated Hospital of Southern Medical University