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A registration study of sepsis patients in the Third Affiliated Hospital of Southern Medical University

The role of platelet mitochondrial dysfunction in the early diagnosis and condition determination of clinical sepsis patients

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900026723
Enrollment
Unknown
Registered
2019-10-20
Start date
2019-10-18
Completion date
Unknown
Last updated
2021-11-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sepsis

Interventions

Healthy person group:nothing
Sepsis group:nothing
Septic shock group:nothing

Sponsors

the Third Affiliated Hospital of Southern Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Patients with sepsis 3.0

Exclusion criteria

Exclusion criteria: Patients younger than 18 years old, pregnant or lactating, serious hematological diseases, malignant tumors, use of drugs affecting platelet function within 2 weeks, active bleeding leads to hemodynamic instability, meeting the enrollment conditions for more than 24 hours;

Design outcomes

Primary

MeasureTime frame
Ultrastructure of platelet mitochondria;Mitochondrial membrane potentia;Adenosine triphosphate content in platelets;The state of mitochondrial permeability control in platelets;—

Secondary

MeasureTime frame
Length of stay in intensive care;Mechanical ventilation time;Sequential Organ Failure Assessment, SOFA;28 day mortality; acute physiology and chronic health evaluation II, APACHE-II;Number of organ failure;Time of multiple organ dysfunction;—

Countries

China

Contacts

Public ContactHong Yang

The Third Affiliated Hospital of Southern Medical University

13512756677@163.com+86 13512756677

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026