Mood Disorders, psychological and physiological disorders and psychosomatic diseases
Conditions
Interventions
paients with depression group:venlafaxine treatment for depression group
Sponsors
Shanxi Medical University
Eligibility
Sex/Gender
All
Age
30 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Patients with depression: Aged 30 to 60 years; The Han nationality; Right-handedness; Starting without treatment; Meet the diagnostic criteria for major depressive disorder in DSM-IVHAMD-17 >=17; Patients and their families agree to participate in the study. 2. Normal healthy people: Aged 30 to 60 years; The Han nationality; Right-handedness; Voluntary consent to participate in the study.
Exclusion criteria
Exclusion criteria: 1. Patients with depression: Major physical illness or a history of brain trauma; Other neuropsychiatric disorders; Antidepressant, antipsychotics or no convulsive electroshock treatment in the last 1 month; Pregnant or lactating women. 2. Normal healthy people: Major physical illness or a history of brain trauma; With neuropsychiatric diseases; Two members of three generations of a family history of mental illness.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| miR-34b/c;mRNA / protein expression; | — |
Countries
China
Contacts
Public ContactSun Ning
Shanxi Medical University
Outcome results
None listed