Ischemic stroke
Conditions
Interventions
Group A:0.5 W/cm2 TUS
Group B:0.75 W/cm2 TUS
Group C:sham TUS(Non-working mode)
Sponsors
The Second Affiliated Hospital of Xi'an Jiaotong University
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. First ever subacute ischemic stroke, conformed to the "guidelines for diagnosis and treatment of acute ischemic stroke in China 2014" and confirmed by CT or MRI imaging scan; 2. 1 months after the stroke event; 3. Aged 18-85 years; 4. Residual upper limb impairment; 5. Brunnstrom motor recovery stages (BMRS) of the affected side upper limb and hand at least stage III; 6. Conscious, vital signs stable and ability to cooperate with training; 7. Commit to follow the research procedures and cooperate with the implementation of the whole research process; 8. Commit to following lifestyle tips during the research 9. Willing to sign the informed consent for this study.
Exclusion criteria
Exclusion criteria: 1. Consciousness disorder, cognitive dysfunction, mental disorder or mixed aphasia; 2. Hemorrhagic cerebral infarction; 3. Intractable epilepsy; 4. With serious dysfunction of liver, kidney, heart and other important organs; 5. Severe shoulder pain or severe limitation of range of motion in shoulder and elbow joints; 6. With musculoskeletal disorders that affect upper limb movement disorders; 7. Internal cardiac pacemaker or intracranial implantation of other metal medical devices; 8. Severe impairment of vision or hearing; 9. Woman who is pregnant or nursing; 10. The absence of a skull; 11. The investigator considers that there are any conditions that could harm the subject or cause the subject to fail to meet or perform the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the Wolf Motor Function Test;Jebsen Hand Function Test, JHFT; | — |
Secondary
| Measure | Time frame |
|---|---|
| the Upper Extremity Section of the Fugl-Meyer Assessment, FMA-UE;Motion Evoked Potential;resting motor threshold;active motor threshold;cortex silent period;mini-mentalstateexamination;Montreal cognitive assessment;event-related potential; | — |
Countries
China
Contacts
Public ContactZhang qiaojun
The Second Affiliated Hospital of Xi'an Jiaotong University
Outcome results
None listed